"Depressive disorders make one feel exhausted, worthless, helpless, and hopeless and it is important to realize that these negative views are part of the depression and typically do not accurately reflect the actual circumstances."

"A study supported by the National Institute of Mental Health (NIMH) found that CBT led to remission in nearly 65 percent of cases, a higher rate than either supportive therapy or family therapy."

Symptoms of Depression and Mania


Not everyone who is depressed or manic experiences every symptom. Some people experience only a few; some people suffer many. The severity of symptoms varies among individuals and also over time.

Depression

* Persistent sad, anxious, or empty mood.
* Feelings of hopelessness or pessimism.
* Feelings of guilt, worthlessness, or helplessness.
* Loss of interest or pleasure in hobbies and activities that were once enjoyable, including sex.
* Decreased energy, fatigue; feeling slowed down.
* Difficulty concentrating, remembering, or making decisions.
* Trouble sleeping, early morning awakening, or oversleeping.
* Changes in appetite and/or weight.
* Thoughts of death or suicide, or suicide attempts.
* Restlessness or irritability.
* Persistent physical symptoms, such as headaches, digestive disorders, and chronic pain that do not respond to routine treatment.

Mania

* Abnormal or excessive elation.
* Unusual irritability.
* Decreased need for sleep.
* Grandiose notions.
* Increased talking.
* Racing thoughts.
* Increased sexual desire.
* Markedly increased energy.
* Poor judgment.
* Inappropriate social behavior.

"Medication as a first-line course of treatment should be considered for children and adolescents with severe symptoms that would prevent effective psychotherapy, those who are unable to undergo psychotherapy, those with psychosis, and those with chronic or recurrent episodes."

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"As research continues to reveal that depressive disorders are real and treatable, and no greater a sign of weakness than cancer or any other serious illness, more and more men with depression may feel empowered to seek treatment and find improved quality of life."

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"The interaction of tyramine with MAOIs can bring on a hypertensive crisis, a sharp increase in blood pressure that can lead to a stroke."

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"Some people with milder forms of depression may do well with psychotherapy alone and people with moderate to severe depression most often benefit from antidepressants, but most do best with combined treatment: medication to gain relatively quick symptom relief and psychotherapy to learn more effective ways to deal with life's problems, including depression."

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"We still do not know if depression is truly less common among men, or if men are just less likely than women to recognize, acknowledge, and seek help for depression."

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"The more sedating antidepressants are generally taken at bedtime to help sleep and minimize daytime drowsiness."