"Alcohol including wine, beer, and hard liquoror street drugs may reduce the effectiveness of antidepressants and should be avoided."

"Medication as a first-line course of treatment should be considered for children and adolescents with severe symptoms that would prevent effective psychotherapy, those who are unable to undergo psychotherapy, those with psychosis, and those with chronic or recurrent episodes."

Symptoms of Depression and Mania


Not everyone who is depressed or manic experiences every symptom. Some people experience only a few; some people suffer many. The severity of symptoms varies among individuals and also over time.

Depression

* Persistent sad, anxious, or empty mood.
* Feelings of hopelessness or pessimism.
* Feelings of guilt, worthlessness, or helplessness.
* Loss of interest or pleasure in hobbies and activities that were once enjoyable, including sex.
* Decreased energy, fatigue; feeling slowed down.
* Difficulty concentrating, remembering, or making decisions.
* Trouble sleeping, early morning awakening, or oversleeping.
* Changes in appetite and/or weight.
* Thoughts of death or suicide, or suicide attempts.
* Restlessness or irritability.
* Persistent physical symptoms, such as headaches, digestive disorders, and chronic pain that do not respond to routine treatment.

Mania

* Abnormal or excessive elation.
* Unusual irritability.
* Decreased need for sleep.
* Grandiose notions.
* Increased talking.
* Racing thoughts.
* Increased sexual desire.
* Markedly increased energy.
* Poor judgment.
* Inappropriate social behavior.

"Depression can exist before the diagnosis of cancer or may develop after the cancer is identified."

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"As research continues to reveal that depressive disorders are real and treatable, and no greater a sign of weakness than cancer or any other serious illness, more and more men with depression may feel empowered to seek treatment and find improved quality of life."

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"Many people use St John's wort without consulting a physician."

Health Insurance Virginia

"Some drugs, like alcohol (wine, beer, and hard liquor) or street drugs, may reduce the effectiveness of antidepressants and should be avoided."

Anthem Health Insurance

"NIMH-sponsored studies estimate that 6 percent of 9- to 17-year-olds in the United States and almost 10 percent of American adults, or about 19 million people age 18 and older, experience some form of depression every year."

Medical Health

"The more sedating antidepressants are generally taken at bedtime to help sleep and minimize daytime drowsiness."