"ECT often is effective in cases where antidepressant medications do not provide sufficient relief of symptoms."

"Today in Germany, Hypericum is used in the treatment of depression more than any other antidepressant, however, the scientific studies that have been conducted on its use have been short-term and have used several different doses."

Causes of Depression


Substantial evidence from neuroscience, genetics, and clinical investigation shows that depressive illnesses are disorders of the brain. However, the precise causes of these illnesses continue to be a matter of intense research.

Modern brain imaging technologies reveal that, in depression, neural circuits responsible for the regulation of moods, thinking, sleep, appetite, and behavior fail to function properly, and critical neurotransmitterschemicals that brain cells use to communicate are out of balance. Studies of brain chemistry, including the effects of antidepressant medications, continue to inform our understanding of the biochemical processes involved in depression.

In some families, depressive disorders seem to occur generation after generation; however, they can also occur in people with no family history of these illnesses. Genetics research indicates that risk for depression results from the influence of multiple genes acting together with environmental or other nongenetic factors.
Very often, a combination of genetic, cognitive, and environmental factors is involved in the onset of a depressive disorder. Trauma, loss of a loved one, a difficult relationship, a financial problem, or any stressful change in life patterns, whether the change is unwelcome or desired, can trigger a depressive episode in vulnerable individuals. Later episodes of depression may occur without an obvious cause.

"Persons with cancer, their families and friends, and even their physicians and oncologists (physicians specializing in cancer treatment) may misinterpret depression's warning signs, mistaking them for inevitable accompaniments to cancer."

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"Treatment for Minor DepressionIn a new approach to research on minor depression, the National Institutes of Health (NIH) has launched a four-year study to determine the safety and effectiveness of St John's wort, a common herbal supplement, and citalopram, a standard antidepressant, compared to placebo."

Anxiety And Depression Support Group

"Many people with dysthymia also experience major depressive episodes at some time in their lives."

Vascular Depression In The Elderly

"In focus groups conducted by the National Institute of Mental Health (NIMH) to assess depression awareness, men described their own symptoms of depression without realizing that they were depressed."

Depression Symptoms

"Studies of brain chemistry, including the effects of antidepressant medications, continue to inform our understanding of the biochemical processes involved in depression."

Chronic Depression Pain

"Genetics research indicates that risk for depression results from the influence of multiple genes acting together with environmental or other nongenetic factors."